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The portion of the cell in the upper part of the illustration is an A cell.It contains characteristic granules (arrows) showing a dense spherical core surrounded by a clear area and then a membrane. Theguinea pig tissue cage model perfectly simulates the clinical situation, that is, very lownumbers of microorganisms lead to permanent implant-associated infection, which neverspontaneously heals [4, 10, 44]. They migrate with the absorptive and gob-let cells but at a slower rate.
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